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Best Performing Major Pharmaceuticals Stocks of 2021 for USA

Updated Jul 12, 2021

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Among the various stocks of the U.S.-listed companies belonging to the Major Pharmaceuticals sector or business segment, which ones have been the front-runners in terms of generating the highest returns for the investors? Here is the following list comprising of those top 10 America-listed stocks of the 'Major Pharmaceuticals' sector, industry or business segment (or index), which have generated the best returns in terms of price changes between the end of previous year and the date of writing.

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Top Performing Major Pharmaceuticals StocksAll Major Pharmaceuticals StocksTop Major Pharmaceuticals Stocks for Q3 2021

Top Major Pharmaceuticals Stocks With Highest Returns

The following list presents stocks of the companies which belong to the broader Major Pharmaceuticals sector or the stock market index, their corresponding prices as of given date, and the percentage gains realized:
 1) KemPharm, Inc. (KMPH) 2) Cassava Sciences, Inc. (SAVA) 3) Onconova Therapeutics, Inc. (ONTX) 4) Novan, Inc. (NOVN) 5) PDS Biotechnology Corporation (PDSB)
 6) Prothena Corporation plc (PRTA) 7) Oramed Pharmaceuticals Inc. (ORMP) 8) Aclaris Therapeutics, Inc. (ACRS) 9) Acura Pharmaceuticals, Inc. (ACUR) 10) Sunesis Pharmaceuticals, Inc. (SNSS)

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Top Performing Major Pharmaceuticals StocksAll Major Pharmaceuticals StocksTop Major Pharmaceuticals Stocks for Q3 2021

Performance of Top Major Pharmaceuticals Stocks

Here's a look at the basic details and how the above mentioned stocks fared during the period:

KemPharm

KemPharm, Inc., incorporated on May 28, 2014, is a clinical-stage specialty pharmaceutical company. The Company is engaged in the discovery and development of prodrugs. The Company uses its Ligand Activated ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of KemPharm.
The Iowa, IA-headquartered company KemPharm, Inc. (KMPH) is ranked number one among the best performing stocks of Major Pharmaceuticals of 2021. The Healthcare sector business falls under the Major Pharmaceuticals industrial sub-sector. Since the start of the year 2021, the stock price of KemPharm has changed by 1736.11 percent, which is calculated based on the previous year's closing price of $0.72 per share and year-to-date closing price of $13.22 per share as of writing. The market value of the company as indicated by its market-cap changed from $3.27 million to $448.08 million during the same period. Along with Major Pharmaceuticals, the company is also in the business of Health Care, Biotechnology, Biotech, Healthcare, Wilshire 5000, among other usual products and services. KemPharm continues to be a leading constituent of many major stock market indexes like Wilshire 5000 index, and a few other larger indexes which are part of the stock market.

Cassava Sciences, Inc.

Cassava Sciences, Inc., a clinical stage biotechnology company, develops drugs for neurodegenerative diseases. Its lead therapeutic product candidate is ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Cassava Sciences, Inc..
The Austin, United States-based Healthcare sector company Cassava Sciences, Inc. (SAVA) holds the number two spot among the best performing stocks of the Major Pharmaceuticals sector. Classified as the Major Pharmaceuticals business, the stock price of Cassava Sciences, Inc. ended the previous year at a price of $6.82 per share while it reached the level of $99.32 apiece as of Jul 12, 2021 translating to a percentage change in stock price of 1356.3%. As of writing, the company's market-cap value stands at $3.97 billion.

Onconova Therapeutics

Onconova Therapeutics, Inc., incorporated on December 22, 1998, is a clinical-stage biopharmaceutical company. The Company operates through the identification and development of oncology therapeutics segment. It is focused on discovering ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Onconova Therapeutics.
During the given months of the year 2021, Onconova Therapeutics, Inc. (ONTX) was successful in generating YTD returns of 1183.81 percentage which helped it gain the number three spot in the list of the top performing stocks which generated maximum returns during year 2021 till date. As of December of the previous year, the stock of the Pennsylvania, PA-based Onconova Therapeutics closed at a price of $0.47 per share, while it traded at a price of $5.98 per share as of Jul 12, 2021. The company's market cap changed from $86.15 million to $94.37 million during the same period YTD. It ranks as a key constituent of major indexes that include Wilshire 5000 index, and several other broader level multi-cap market indicators. The company is classified under the Healthcare industry sector and further specialized as a Major Pharmaceuticals sector business.

Novan

Novan, Inc. is a late-stage pharmaceutical company. The Company is engaged in the development and commercialization of therapies using its nitric oxide platform. The Company develops product candidates using its ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Novan.
Rank number four in the coveted list is held by Novan, Inc. (NOVN) for being among the top performing stocks of 2021. Headquartered in North Carolina, NC, the Healthcare sector company is categorized under the industrial sub-sector of Major Pharmaceuticals. Since the start of the year 2021, stock of Novan has so far gained 1015.62 percentage, based on the previous year's closing price of $0.81 per share and year-to-date price of $9.07 per share. During the same period, the market capitalization of the company changed from $115.05 million to $170.58 million.

PDS Biotechnology Corporation

PDS Biotechnology Corporation, a clinical-stage biopharmaceutical company, focuses on developing multifunctional cancer immunotherapies. Its lead product ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of PDS Biotechnology Corporation.
At number five in the list of top stocks stands PDS Biotechnology Corporation (PDSB), which saw a change in its stock price from the level of $2.14 apiece during previous year December end to the price of $10.02 per share as of Jul 12, 2021. It translates to a change of 368.22 percentage. The Florham Park, United States-headquartered Healthcare sector company also saw its market value change from $0 million to $284.23 million.

Prothena

Prothena Corporation Public Limited Company, incorporated on September 26, 2012, is a global biotechnology company. The Company is focused on the discovery, development and commercialization of immunotherapies for the treatment ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Prothena.
Based on the market-cap change from $479.46 million to $2.4 billion during the given months of the year 2021 and the share price change from $12.01 per share to a price of $54.39 per share as of Jul 12, 2021, Prothena Corporation plc (PRTA) was successful in generating YTD returns of 352.87 percentage. Standing at the number six rank in the top performing list of Major Pharmaceuticals stocks, the California, CA-based Prothena is categorized as the Major Pharmaceuticals sub-sector business which falls under the larger Healthcare sector. It is also a part of few famous stock indexes that are used to track the overall performance of the stock market. They include Wilshire 5000 index, and a few more broader-level indexes that are actively tracked in the market.

Oramed Pharma

Oramed Pharmaceuticals Inc. (Oramed) is engaged in the field of oral delivery solutions for drugs and vaccines presently delivered via injection. OramedĘs flagship product, an orally ingestible insulin capsule in ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Oramed Pharma.
Oramed Pharmaceuticals Inc. (ORMP) has moved by 220.75 percentage over the given period of 2021-YTD, helping it gain a place at number seven among the top performing stocks. The Healthcare sector company managed to achieve the feat as its stock price changed from $4.24 apiece to the price of $13.6 per share between the end of December of the previous year and Jul 12, 2021. The smart run of the Israel-based Major Pharmaceuticals sector company lead to a handsome gain in its marketcap which changed from $100.38 million to $422.04 million over the same duration.

Aclaris Therapeutics

Aclaris Therapeutics, Inc., incorporated on July 13, 2012, is a clinical-stage specialty pharmaceutical company. The Company is focused on identifying, developing and commercializing differentiated drugs for the treatment of dermatological ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Aclaris Therapeutics.
Aclaris Therapeutics (ACRS) generated percentage returns of 173.72 percent during the 2021 year-to-date. Its returns are based on the share price which moved from $6.47 per share from the previous year-end to the price of $17.71 per share as of Jul 12, 2021. The company's value, as indicated by the market-cap figure, changed from $277.69 million to $1.05 billion during the same period.
The company is categorized as a Healthcare speciality business with further classification in the Major Pharmaceuticals sub-category. Based in Pennsylvania, PA, the YTD performance of the Major Pharmaceuticals sector also fared better than that of the returns generated by some of the closley tracked stock market indexes. The company is a part of Wilshire 5000 index, and a few other wider multi-cap stock market indexes.

Acura Pharma

Acura Pharmaceuticals, Inc., incorporated on April 10, 1935, is a pharmaceutical company. The Company is engaged in the research, development and commercialization of technologies and products intended to address medication ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Acura Pharma.
The number nine spot in the list of top performing stocks of the Major Pharmaceuticals sector is taken by Acura Pharmaceuticals, Inc. (ACUR). The company's stock price changed from $0.21 per share at the end of December of the previous year to the price of $0.57 per share as of writing. Overall, the stock managed to realized price change of 171.9 percent during the given time period. The corresponding change in the market capitalization value of the Palatine, IL-based Healthcare sector company was from $4.55 million to $37.17 million. Being ranked in the top 10 best performing stocks of the Major Pharmaceuticals sector, the company also succeeded in outperforming the returns generated by some of the popular stock market indexes.

Sunesis Pharma

Sunesis Pharmaceuticals, Inc., incorporated on February 10, 1998, is a biopharmaceutical company. The Company focuses on the development and commercialization of its pipeline of oncology therapeutics for the treatment of ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Sunesis Pharma.
The California, CA-based Sunesis Pharmaceuticals, Inc. (SNSS) belongs to the Healthcare sector and is categorized as a Major Pharmaceuticals company. The stock of Sunesis Pharma ended the previous year at a price of $1.99 per share. As of Jul 12, 2021, the stock price has reached $5.32 apiece, which indicates a change of 167.34 percent making the company rank among the top performing stocks of the Major Pharmaceuticals for the year 2021 till date. At the end of the last year, company's market capitalization stood at $36.01 million. It has now changed to $96.34 million as of writing. Sunesis Pharma continues to be a leading constituent of many major stock market indexes like Wilshire 5000 index, and several other broader level multi-cap market indicators.
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