Best Performing Healthcare Penny Stocks of 2022 USA

Updated Jun 13, 2022

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The healthcare sector often produces many high return generating companies, as stocks of the companies working in the pharma, drug discovery, research or associated business have the potential to emerge as winners. Say, if after few years of research work, a small drug research company is able to develop a cure for an ailment or disease which can result in big profits due to patent, copyright and other clauses. The stock price of such a company will shoot through the roof the day it tastes success. Pharma and health sector offers this great potential for producing many multi-bagger stocks. Therefore, investors who are good to make such small-priced bets on such economical-looking, low-cost healthcare stocks do so in expectations of high rewards in the future. These constitute the healthcare penny stocks.
However, one must note that not all such penny stock investments taste success. Majority of them fail, but those which do win offer big potential of not only recouping the losses of losers but also offering great surplus profits.
Penny stocks are those which are trading at a per share price of below $5. Among the various stocks of the U.S.-listed companies belonging to the Healthcare Penny segment, which ones have been the front-runners in terms of generating the highest returns for the investors? Here is the following list comprising of those top 10 America-listed stocks of the 'Healthcare Penny' sector, industry or business segment (or index), which have generated the best returns in terms of price changes between the end of previous year and the date of writing.

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Top Performing Healthcare Penny StocksAll Healthcare Penny StocksTop Healthcare Penny Stocks for Q3 2022

Top Healthcare Penny Stocks With Highest Returns

The following list presents stocks of the companies which belong to the broader Healthcare Penny sector or the stock market index, their corresponding prices as of given date, and the percentage gains realized:
 1) Neptune Technologies and Bioresources Inc (NEPT) 2) Histogen Inc. (HSTO) 3) Surgalign Holdings, Inc. (SRGA) 4) Tonix Pharmaceuticals Holding Corp. (TNXP) 5) PolarityTE, Inc. (PTE)
 6) CASI Pharmaceuticals, Inc. (CASI) 7) Evoke Pharma, Inc. (EVOK) 8) AzurRx BioPharma, Inc. (AZRX) 9) Rockwell Medical, Inc. (RMTI) 10) Baudax Bio, Inc. (BXRX)

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Top Performing Healthcare Penny StocksAll Healthcare Penny StocksTop Healthcare Penny Stocks for Q3 2022

Performance of Top Healthcare Penny Stocks

Here's a look at the basic details and how the above mentioned stocks fared during the period:

Neptune and Bioresources

Neptune Technologies & Bioressources Inc. is a solution provider of omega-3s and other functional ingredients to branded marketers in the nutraceutical industry, primarily in North America. The Company is engaged ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Neptune and Bioresources.
Neptune Technologies and Bioresources Inc (NEPT) has moved by 770.15 percentage over the given period of 2022-YTD, helping it gain a place at number one among the top performing stocks. The Healthcare sector company managed to achieve the feat as its stock price changed from $0.37 apiece to the price of $3.21 per share between the end of December of the previous year and Jun 13, 2022. The smart run of the Canada-based Major Pharmaceuticals sector company lead to a handsome gain in its marketcap which changed from $62.38 million to $15.75 million over the same duration.

Histogen Inc.

Histogen Inc., a clinical-stage therapeutics company, focuses on developing therapeutics based upon the products of fibroblast cells grown under simulated ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Histogen Inc..
The number two spot in the list of top performing stocks of the Healthcare Penny sector is taken by Histogen Inc. (HSTO). The company's stock price changed from $0.33 per share at the end of December of the previous year to the price of $2.22 per share as of writing. Overall, the stock managed to realized price change of 582.66 percent during the given time period. The corresponding change in the market capitalization value of the San Diego, United States-based Healthcare sector company was from $16.24 million to $5.54 million. Being ranked in the top 10 best performing stocks of the Healthcare Penny sector, the company also succeeded in outperforming the returns generated by some of the popular stock market indexes.

Surgalign Holdings, Inc.

Surgalign Holdings, Inc., a medical technology company, develops, manufactures, distributes, and markets spine implants worldwide. It offers products for ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Surgalign Holdings, Inc..
Surgalign Holdings, Inc. (SRGA) generated percentage returns of 450.94 percent during the 2022 year-to-date. Its returns are based on the share price which moved from $0.72 per share from the previous year-end to the price of $3.98 per share as of Jun 13, 2022. The company's value, as indicated by the market-cap figure, changed from $100.56 million to $26.36 million during the same period.
The company is categorized as a Healthcare speciality business with further classification in the Medical Devices sub-category. Based in Deerfield, United States, the YTD performance of the Healthcare Penny sector also fared better than that of the returns generated by some of the closley tracked stock market indexes.

Tonix Pharma Holding

Tonix Pharmaceuticals Holding Corp. (Tonix), incorporated on November 16, 2007, is a clinical-stage pharmaceutical company. The Companys drug development programs are directed toward disorders affecting the central nervous system (CNS), ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Tonix Pharma Holding.
The New York, NY-based Healthcare sector company Tonix Pharmaceuticals Holding Corp. (TNXP) holds the number four spot among the best performing stocks of the Healthcare Penny sector. Classified as the Major Pharmaceuticals business, the stock price of Tonix Pharma Holding ended the previous year at a price of $0.36 per share while it reached the level of $1.77 apiece as of Jun 13, 2022 translating to a percentage change in stock price of 386.66%. As of writing, the company's market-cap value stands at $33.17 million. Few leading stock market index includes Tonix Pharma Holding in their constituent list. They include Wilshire 5000 index, and a few other larger indexes which are part of the stock market.

PolarityTE

PolarityTE, Inc., a biotechnology and regenerative biomaterials company, focuses on discovering, designing, and developing a range of regenerative tissue products and biomaterials for the fields of medicine, bi ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of PolarityTE.
Based on the market-cap change from $36.71 million to $8.2 million during the given months of the year 2022 and the share price change from $0.45 per share to a price of $2.04 per share as of Jun 13, 2022, PolarityTE, Inc. (PTE) was successful in generating YTD returns of 355.26 percentage. Standing at the number five rank in the top performing list of Healthcare Penny stocks, the Salt Lake City, UT-based PolarityTE is categorized as the Healthcare sub-sector business which falls under the larger Healthcare sector. It is also a part of few famous stock indexes that are used to track the overall performance of the stock market. They include Wilshire 5000 index, and a few more broader-level indexes that are actively tracked in the market.

CASI Pharma

CASI Pharmaceuticals, Inc., incorporated on September 18, 1991, is a biopharmaceutical company. The Company is focused on the acquisition, development and commercialization of therapeutics for cancer and other medical needs. ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of CASI Pharma.
The Maryland, MD-headquartered company CASI Pharmaceuticals, Inc. (CASI) is ranked number six among the best performing stocks of Healthcare Penny of 2022. The Healthcare sector business falls under the Biotech Biological Products industrial sub-sector. Since the start of the year 2022, the stock price of CASI Pharma has changed by 268.56 percent, which is calculated based on the previous year's closing price of $0.82 per share and year-to-date closing price of $3.01 per share as of writing. The market value of the company as indicated by its market-cap changed from $114.17 million to $40.96 million during the same period. Along with Healthcare Penny, the company is also in the business of Health Care, Biotech Biological Products, Biotech Products, Biotechnology, Biotech, Healthcare, Wilshire 5000, among other usual products and services. CASI Pharma continues to be a leading constituent of many major stock market indexes like Wilshire 5000 index, and a few other larger indexes which are part of the stock market.

Evoke Pharma

Evoke Pharma, Inc., incorporated on January 29, 2007, is a specialty pharmaceutical company. The Company is focused primarily on the development of drugs to treat gastrointestinal (GI) disorders and diseases. ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Evoke Pharma.
During the given months of the year 2022, Evoke Pharma, Inc. (EVOK) was successful in generating YTD returns of 263.42 percentage which helped it gain the number seven spot in the list of the top performing stocks which generated maximum returns during year 2022 till date. As of December of the previous year, the stock of the California, CA-based Evoke Pharma closed at a price of $0.58 per share, while it traded at a price of $2.09 per share as of Jun 13, 2022. The company's market cap changed from $18.78 million to $7.79 million during the same period YTD. It ranks as a key constituent of major indexes that include Wilshire 5000 index, and several other broader level multi-cap market indicators. The company is classified under the Healthcare industry sector and further specialized as a Major Pharmaceuticals sector business.

AzurRx BioPharma

AzurRx BioPharma, Inc., incorporated on January 30, 2014, is a clinical development-stage biopharmaceutical company. The Company is engaged in the research and development of non-systemic biologics for the treatment of ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of AzurRx BioPharma.
Rank number eight in the coveted list is held by AzurRx BioPharma, Inc. (AZRX) for being among the top performing stocks of 2022. Headquartered in New York, NY, the Healthcare sector company is categorized under the industrial sub-sector of Biotech. Since the start of the year 2022, stock of AzurRx BioPharma has so far gained 255.67 percentage, based on the previous year's closing price of $0.97 per share and year-to-date price of $3.45 per share. During the same period, the market capitalization of the company changed from $29.5 million to $34.38 million.

Rockwell Medical

Rockwell Medical, Inc. (Rockwell), incorporated on October 25, 1996, is a biopharmaceutical company targeting end-stage renal disease (ESRD) and chronic kidney disease (CKD) with products and services for the treatment ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Rockwell Medical.
At number nine in the list of top stocks stands Rockwell Medical, Inc. (RMTI), which saw a change in its stock price from the level of $0.41 apiece during previous year December end to the price of $1.37 per share as of Jun 13, 2022. It translates to a change of 234.15 percentage. The Michigan, MI-headquartered Healthcare sector company also saw its market value change from $38.53 million to $13.41 million. The Biotech-Electromedical Electrotherapeutic Apparatus specialist also managed to outperform some of the major stock market indexes of which it is a part of. They include the Wilshire 5000 index, and a handful of other multi-capitalization indexes.

Baudax Bio

Baudax Bio, Inc., a pharmaceutical company, develops and commercializes products for hospital and other acute care settings. Its lead product candidate is ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Baudax Bio.
The Malvern, Pennsylvania-based Baudax Bio, Inc. (BXRX) belongs to the Healthcare sector and is categorized as a Biotechnology company. The stock of Baudax Bio ended the previous year at a price of $0.22 per share. As of Jun 13, 2022, the stock price has reached $0.68 apiece, which indicates a change of 204.7 percent making the company rank among the top performing stocks of the Healthcare Penny for the year 2022 till date. At the end of the last year, company's market capitalization stood at $18.87 million. It has now changed to $4.37 million as of writing.
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