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Best Performing Biotech Stocks of 2021 for USA

Updated Oct 1, 2021

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Biotech, or biotechnology, is defined as the exploitation and use of biological processes for industrial, commercial and other requirements, especially the genetic manipulation of microorganisms for the generation, production and development of medicinal elements like antibiotics and hormones which can be used for therapeutic use. It is the technology that uses biological systems, living organisms or their parts to build and develop different products. The specialized sub-sector falls within the larger health care sector and involves activities like drug development, research, manufacturing and marketing in the field of biotech.
Among the big basket of Biotech stocks, which ones generated the top returns this year? Which of those figured among the winners in the long list of Biotech stocks?
This article provides a list of Biotech stocks which have generated the highest returns in the year 2021 so far. till date of writing. The list is prepared based on the percentage returns generated by the individual Biotech stocks between the end of the previous year and Oct 1, 2021, and the top 10 return generating Biotech stocks are listed below.

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Top Performing Biotech StocksAll Biotech StocksAll Biotech Mutual FundsAll Biotech ETFsTop Dividend-paying Biotech StocksTop Biotech Stocks for Q4 2021

Top Biotech Stocks With Highest Returns

The following list presents stocks of the companies which belong to the broader Biotech sector or the stock market index, their corresponding prices as of given date, and the percentage gains realized:
 1) KemPharm, Inc. (KMPH) 2) Novan, Inc. (NOVN) 3) Cassava Sciences, Inc. (SAVA) 4) Onconova Therapeutics, Inc. (ONTX) 5) Acorda Therapeutics, Inc. (ACOR)
 6) PDS Biotechnology Corporation (PDSB) 7) Acasti Pharma, Inc. (ACST) 8) Prothena Corporation plc (PRTA) 9) Oramed Pharmaceuticals Inc. (ORMP) 10) Entera Bio Ltd. (ENTX)
There's more... See price performance, YTD-gains, market-cap and other details of all the 541 Biotech stocks with sorting features in a tabular format.
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Alternatively, one can also explore the List of Top Biotech ETFs.

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Top Performing Biotech StocksAll Biotech StocksAll Biotech Mutual FundsAll Biotech ETFsTop Dividend-paying Biotech StocksTop Biotech Stocks for Q4 2021

Performance of Top Biotech Stocks

Here's a look at the basic details and how the above mentioned stocks fared during the period:

KemPharm

KemPharm, Inc., incorporated on May 28, 2014, is a clinical-stage specialty pharmaceutical company. The Company is engaged in the discovery and development of prodrugs. The Company uses its Ligand Activated ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of KemPharm.
The Iowa, IA-headquartered company KemPharm, Inc. (KMPH) is ranked number one among the best performing stocks of Biotech of 2021. The Healthcare sector business falls under the Major Pharmaceuticals industrial sub-sector. Since the start of the year 2021, the stock price of KemPharm has changed by 1190.28 percent, which is calculated based on the previous year's closing price of $0.72 per share and year-to-date closing price of $9.29 per share as of writing. The market value of the company as indicated by its market-cap changed from $3.27 million to $326.58 million during the same period. Along with Biotech, the company is also in the business of Health Care, Major Pharmaceuticals, Biotechnology, Healthcare, Wilshire 5000, among other usual products and services. KemPharm continues to be a leading constituent of many major stock market indexes like Wilshire 5000 index, and a few other larger indexes which are part of the stock market.

Novan

Novan, Inc. is a late-stage pharmaceutical company. The Company is engaged in the development and commercialization of therapies using its nitric oxide platform. The Company develops product candidates using its ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Novan.
During the given months of the year 2021, Novan, Inc. (NOVN) was successful in generating YTD returns of 902.46 percentage which helped it gain the number two spot in the list of the top performing stocks which generated maximum returns during year 2021 till date. As of December of the previous year, the stock of the North Carolina, NC-based Novan closed at a price of $0.81 per share, while it traded at a price of $8.15 per share as of Oct 1, 2021. The company's market cap changed from $115.05 million to $153.33 million during the same period YTD. The company is classified under the Healthcare industry sector and further specialized as a Major Pharmaceuticals sector business.

Cassava Sciences, Inc.

Cassava Sciences, Inc., a clinical stage biotechnology company, develops drugs for neurodegenerative diseases. Its lead therapeutic product candidate is ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Cassava Sciences, Inc..
Rank number three in the coveted list is held by Cassava Sciences, Inc. (SAVA) for being among the top performing stocks of 2021. Headquartered in Austin, United States, the Healthcare sector company is categorized under the industrial sub-sector of Major Pharmaceuticals. Since the start of the year 2021, stock of Cassava Sciences, Inc. has so far gained 787.39 percentage, based on the previous year's closing price of $6.82 per share and year-to-date price of $60.52 per share. During the same period, the market capitalization of the company changed from $0 million to $2.42 billion.

Onconova Therapeutics

Onconova Therapeutics, Inc., incorporated on December 22, 1998, is a clinical-stage biopharmaceutical company. The Company operates through the identification and development of oncology therapeutics segment. It is focused on discovering ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Onconova Therapeutics.
At number four in the list of top stocks stands Onconova Therapeutics, Inc. (ONTX), which saw a change in its stock price from the level of $0.47 apiece during previous year December end to the price of $3.66 per share as of Oct 1, 2021. It translates to a change of 685.74 percentage. The Pennsylvania, PA-headquartered Healthcare sector company also saw its market value change from $86.15 million to $76.06 million. The Major Pharmaceuticals specialist also managed to outperform some of the major stock market indexes of which it is a part of. They include the Wilshire 5000 index, and a handful of other multi-capitalization indexes.

Acorda Therapeutics

Acorda Therapeutics, Inc., incorporated on March 17, 1995, is a biopharmaceutical company. The Company focuses on developing therapies that restore function and improve the lives of people with neurological disorders. ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Acorda Therapeutics.
The New York, NY-based Healthcare sector company Acorda Therapeutics, Inc. (ACOR) holds the number five spot among the best performing stocks of the Biotech sector. Classified as the Biotech Biological Products business, the stock price of Acorda Therapeutics ended the previous year at a price of $0.69 per share while it reached the level of $4.64 apiece as of Oct 1, 2021 translating to a percentage change in stock price of 572.37%. As of writing, the company's market-cap value stands at $51.62 million. Few leading stock market index includes Acorda Therapeutics in their constituent list. They include Wilshire 5000 index, and a few other larger indexes which are part of the stock market.

PDS Biotechnology Corporation

PDS Biotechnology Corporation, a clinical-stage biopharmaceutical company, focuses on developing multifunctional cancer immunotherapies. Its lead product ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of PDS Biotechnology Corporation.
PDS Biotechnology Corporation (PDSB) has moved by 566.82 percentage over the given period of 2021-YTD, helping it gain a place at number six among the top performing stocks. The Healthcare sector company managed to achieve the feat as its stock price changed from $2.14 apiece to the price of $14.27 per share between the end of December of the previous year and Oct 1, 2021. The smart run of the Florham Park, United States-based Major Pharmaceuticals sector company lead to a handsome gain in its marketcap which changed from $0 million to $405.61 million over the same duration.

Acasti Pharma

Acasti Pharma Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in developing, clinically studying and marketing new pharmaceutical products to treat human cardiovascular conditions. The Company is involved ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Acasti Pharma.
The number seven spot in the list of top performing stocks of the Biotech sector is taken by Acasti Pharma, Inc. (ACST). The company's stock price changed from $0.33 per share at the end of December of the previous year to the price of $2.01 per share as of writing. Overall, the stock managed to realized price change of 518.46 percent during the given time period. The corresponding change in the market capitalization value of the Canada-based Healthcare sector company was from $31.54 million to $89.02 million. Being ranked in the top 10 best performing stocks of the Biotech sector, the company also succeeded in outperforming the returns generated by some of the popular stock market indexes.

Prothena

Prothena Corporation Public Limited Company, incorporated on September 26, 2012, is a global biotechnology company. The Company is focused on the discovery, development and commercialization of immunotherapies for the treatment ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Prothena.
Prothena (PRTA) generated percentage returns of 489.01 percent during the 2021 year-to-date. Its returns are based on the share price which moved from $12.01 per share from the previous year-end to the price of $70.74 per share as of Oct 1, 2021. The company's value, as indicated by the market-cap figure, changed from $479.46 million to $3.19 billion during the same period.
The company is categorized as a Healthcare speciality business with further classification in the Major Pharmaceuticals sub-category. Based in California, CA, the YTD performance of the Biotech sector also fared better than that of the returns generated by some of the closley tracked stock market indexes. The company is a part of Wilshire 5000 index, and a few other wider multi-cap stock market indexes.

Oramed Pharma

Oramed Pharmaceuticals Inc. (Oramed) is engaged in the field of oral delivery solutions for drugs and vaccines presently delivered via injection. OramedĘs flagship product, an orally ingestible insulin capsule in ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Oramed Pharma.
The Israel-based Oramed Pharmaceuticals Inc. (ORMP) belongs to the Healthcare sector and is categorized as a Major Pharmaceuticals company. The stock of Oramed Pharma ended the previous year at a price of $4.24 per share. As of Oct 1, 2021, the stock price has reached $20.93 apiece, which indicates a change of 393.63 percent making the company rank among the top performing stocks of the Biotech for the year 2021 till date. At the end of the last year, company's market capitalization stood at $100.38 million. It has now changed to $680.52 million as of writing.

Entera Bio

Entera Bio Ltd., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of orally delivered large molecule therapeutics for unmet medical needs. The company's lead product ... see Detailed Company Profile, full Dividend History, and List of ETFs holding the stock of Entera Bio.
Based on the market-cap change from $19.83 million to $137.75 million during the given months of the year 2021 and the share price change from $1.08 per share to a price of $4.79 per share as of Oct 1, 2021, Entera Bio Ltd. (ENTX) was successful in generating YTD returns of 343.52 percentage. Standing at the number ten rank in the top performing list of Biotech stocks, the Jerusalem, -based Entera Bio is categorized as the Healthcare sub-sector business which falls under the larger Healthcare sector.
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