FKnol.com

Financial Knowledge & Information Portal

Simulations Plus (SLP) Company Profile

Updated Apr 18, 2019
Simulations Plus has the following business profile:
Company's Full Name:Simulations Plus, Inc.
Short Name:Simulations Plus
Trading Ticker Symbol:SLP
Primary Exchange:NASDAQ
Headquarter City/Country:California, CA
Primary Industry Sector:Technology
Seconday Sub-sector:EDP Services
Main Business Areas: Technology, EDP Services, Health Information Services
Dividend Payments:Dividend History

Market and Trading Information for Simulations Plus

The following details were available for trading and market data about the stock of Simulations Plus as of writing:
Current Share Price:$22.44
Previous Year's Closing Price:$19.9
Percentage Price Change (YTD):12.76%
Market Cap:$393.04 million
52-week Price Range:$16.26 - $23.95
Dividend Per Share:$0
EPS (TTM):0.41
Price-Earnings (Trailing):54.73
Price-Earnings (Forward):41.56

Company Profile and Business Description for Simulations Plus

Simulations Plus, Inc., incorporated on July 17, 1996, is a provider of simulation and modeling software for pharmaceutical discovery and development. The Company offers its products and services through two business units, including Simulations Plus, Inc. and Cognigen Corporation. The Company also provides consulting services ranging from early drug discovery through preclinical and clinical trial data analysis and reporting to regulatory agencies. The Company offers over seven software products for pharmaceutical research and development, including three simulation programs that provide time-dependent results-based on solving various sets of differential equations: GastroPlus, DDDPlus and MembranePlus; three programs that are based on predicting and analyzing static properties of chemicals: ADMET Predictor, MedChem Designer and MedChem Studio, which is a combination of ADMET Predictor, MedChem Designer and MedChem Studio is called its ADMET Design Suite, and a program that supports data analysis and reporting through its secure cloud called KIWI. The Company's PKPlus software product is used for non-compartmental pharmacokinetic analysis and reporting. The Company distributes its products and offers its services in North America, South America, Europe, Japan, Australia, New Zealand, India, Singapore and the People's Republic of China.

GastroPlus

The Company's GastroPlus product simulates the absorption, pharmacokinetics and pharmacodynamics of drugs administered to humans and animals. The Company offers a Version 9.0 of GastroPlus.

DDDPlus

The Company's DDDPlus software simulates in vitro laboratory experiments used to measure the rate of dissolution of the drug and sometimes the additives (excipients) contained in tablets and capsules under a range of experimental conditions. This software program is used by formulation scientists in industry and the United States Food and Drug Administration (FDA) to understand the physical mechanisms affecting the dissolution rate for various formulations; to reduce the number of cut-and-try attempts to design drug formulations, and to design in vitro dissolution experiments to mimic in vivo conditions.

MembranePlus

The Company's MembranePlus software is similar to DDDPlus. Its MembranePlus laboratory experiments are for measuring permeability of drug-like molecules through various membranes, including various cell cultures, as well as artificially formulated membranes.

PKPlus

The Company's PKPlus software product provides fitting of compartmental and non-compartmental analysis (NCA) pharmacokinetic models for oral and intravenous doses. The Company's PKPlus program provides the level of functionality needed by pharmaceutical industry scientists to generate the analyses and the outputs needed to satisfy regulatory agency requirements for both NCA and compartmental pharmacokinetics.

ADMET Predictor

The Company's ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) Predictor is a chemistry-based computer program that takes molecular structures as inputs and predicts approximately 150 different properties for them at an average rate of over 100,000 compounds per hour on a modern laptop computer. This capability allows chemists to generate estimates for a number of molecular properties without the need to synthesize and test the molecules, or to generate estimates of unknown properties for molecules that have been synthesized. The Company's ADMET Predictor version 7.2 contains updated cytochrome P450 enzyme kinetics models that are integrated into the GastroPlus Version 9.0, for the synergy between predicted properties and physiologically based pharmacokinetics (PBPK) simulations. The Company is focusing on ADMET Predictor 8.0, which features a redesigned interface. The ADMET Modeler subprogram that is integrated into ADMET Predictor enables scientists to use their experimental data to create predictive models.

MedChem Designer

The Company provides MedChem Designer for free to its customers. The free version includes a set of ADMET Predictor property predictions allowing the chemist to modify molecular structures. With a paid ADMET Predictor license, the chemist can see the entire approximately 150 predictions that are available. When coupled with a license for ADMET Predictor, MedChem Designer becomes a de novo molecule design tool for medicinal chemists. With it the scientists can draw molecular structures and have approximately 150 properties for each structure calculated in seconds. The Company's MedChem Designer version 3.0, adds the ability to capture the image of a molecular structure from a range of publication files with a snapshot tool, and then the program automatically converts the graphic image into various computer-based chemical structure files.

MedChem Studio

The Company's MedChem Studio is a tool that is used both for data mining and for de novo design of molecules. In its data-mining role, MedChem Studio facilitates searching of large chemical libraries to find molecules that contain identified substructures, and it enables generation of clusters (classes) of molecules that share common substructures from high-throughput screening (HTS) data. MedChem Studio can be used to create and screen (with ADMET Predictor) various number of molecules down to a few lead candidates. When MedChem Studio is used with ADMET Predictor and MedChem Designer, the programs provide an unmatched capability for chemists to search through large libraries of compounds that have undergone high-throughput screening experiments to find the classes (groups of molecules with a large common part of their structures) and molecules that are active against a particular target. In addition, MedChem Studio can take an interesting (but not acceptable) molecule and, using a range of design algorithms, generate many thousands to millions of analogs (similar new molecules). These molecules can then be screened using ADMET Predictor to find molecules that are both active against the target, as well as acceptable in a range of ADMET properties.

NCE Projects

The Company's New Chemical Entity (NCE) design project is used to design molecules and have them synthesized and tested. The Company has conducted over two NCE design projects, the Company has designed molecules to test against the malaria parasite and in the other it has designed molecules to test against the cyclo-oxygenase-2 (COX-2) enzyme that is the target for Celebrex.

KIWI

The Company's KIWI is a cloud-based Web application that organizes, processes, maintains and communicates the volume of data and results generated by pharmacologists and scientists over the duration of a drug development program. KIWI Version 1.3 provides its user community with access to features that accelerate completion of modeling projects by decreasing run times, and facilitating the comparison and exporting of results across models. These features include comparisons of model parameter estimates and diagnostic plots, export of model run records for regulatory submissions and accelerated infrastructure with the upgrade to the versions of NONMEM and Perl-speaks-NONMEM running in a 64-bit Linux environment.

42505 10th St W

Peer / Competitor Companies of EDP Services Sector

Along with Simulations Plus, Inc., the following other peer (competitor) companies also exist within the same EDP Services - Technology sector whose company profile and dividend history is as follows:

▶ Actua (ACTA): Actua Corporation, formerly ICG Group, Inc., incorporated on February 2, 1999, is a multi-vertical cloud technology company. The Company operates through two segments, which include the vertical cloud segment and ....See Detailed Company Profile  and Dividend History.

▶ Acxiom (ACXM): Acxiom Corporation (Acxiom), incorporated on October 28, 1983, is a technology and enablement services company. The Company operates through three business segments: Marketing Services, Audience Solutions, and Connectivity. The Company ....See Detailed Company Profile  and Dividend History.

▶ Aerohive Networks (HIVE): Aerohive Networks, Inc., incorporated on March 15, 2006, together with its subsidiaries, has designed and developed a cloud-managed mobile networking platform that enables enterprises to deploy and manage a mobile-centric ....See Detailed Company Profile  and Dividend History.

▶ Agilysys (AGYS): Agilysys, Inc., incorporated on February 4, 1963, is a technology company. The Company provides software for point-of-sale (POS), property management, inventory and procurement, workforce management, analytics, document management, and mobile ....See Detailed Company Profile  and Dividend History.

▶ Allscripts Healthcare (MDRX): Allscripts Healthcare Solutions, Inc. (Allscripts), incorporated on July 11, 2000, delivers information technology (IT) solutions and services to help healthcare organizations. The Company operates through three segments: Clinical and Financial ....See Detailed Company Profile  and Dividend History.

▶ Amdocs (DOX): Amdocs Limited, incorporated on September 28, 1988, is a provider of software and services for communications, entertainment and media industry service providers. The Company develops, implements and manages software and ....See Detailed Company Profile  and Dividend History.

▶ Aspen Technology (AZPN): Aspen Technology, Inc., incorporated on March 11, 1998, is a global provider of process optimization software solutions designed to manage and optimize plant and process design, operational performance, and supply ....See Detailed Company Profile  and Dividend History.

▶ Asure Software (ASUR): Asure Software, Inc., incorporated on May 30, 1989, is a global provider of cloud-based software-as-a-service (SaaS) solutions that help companies to bring people, time, space and assets together. The Company ....See Detailed Company Profile  and Dividend History.

▶ Autohome (ATHM): Autohome Inc., incorporated on June 23, 2008, is an online destination for automobile consumers in China. The Company is engaged in the provision of online advertising and dealer subscription services ....See Detailed Company Profile  and Dividend History.

▶ Automatic Data Processing (ADP): Automatic Data Processing, Inc. (ADP), incorporated on June 12, 1961, is a provider of human capital management (HCM) solutions to employers, offering solutions to businesses of various sizes. The Company ....See Detailed Company Profile  and Dividend History.

▶ Bankrate (RATE): Bankrate, Inc., incorporated on April 13, 2011, is a publisher, aggregator and distributor of personal finance content on the Internet. The Company provides consumers personal finance editorial content across multiple ....See Detailed Company Profile  and Dividend History.

▶ Bitauto (BITA): Bitauto Holdings Limited (Bitauto), incorporated on October 21, 2005, is a provider of Internet content and marketing services for Chinas automotive industry. The Companys bitauto.com and taoche.com Websites provide consumers ....See Detailed Company Profile  and Dividend History.

▶ Blucora (BCOR): Blucora, Inc., incorporated on April 9, 1996, is a provider of technology-enabled financial solutions to consumers, small business owners and tax professionals. The Company operates through the Wealth Management and ....See Detailed Company Profile  and Dividend History.

▶ Brightcove (BCOV): Brightcove Inc., incorporated on August 24, 2004, is a global provider of cloud-based services for video. The Companys products and services include Brightcove Video Cloud (Video Cloud), Brightcove Zencoder (Zencoder), ....See Detailed Company Profile  and Dividend History.

▶ CACI International (CACI): CACI International Inc (CACI), incorporated on October 8, 1985, is a simulation technology company. The Company provides information solutions and services. The Company operates through two segments: domestic operations and ....See Detailed Company Profile  and Dividend History.

▶ Callidus Software (CALD): Callidus Software Inc. (Callidus), incorporated on September 6, 1996, is a provider of cloud-based sales, marketing, learning and customer experience solutions. The Companys CallidusCloud enables its customers to manage their ....See Detailed Company Profile  and Dividend History.

▶ Carbonite (CARB): Carbonite, Inc., incorporated on February 10, 2005, provides data protection solutions, including cloud, hybrid and on-premise backup and restore, disaster recovery as a service (DRaaS) and e-mail archiving. The Companys ....See Detailed Company Profile  and Dividend History.

▶ Castlight Health (CSLT): Castlight Health, Inc., incorporated on January 31, 2008, offers a health benefits platform that engages employees to make healthcare decisions, and enables employers to communicate and measure their benefit programs. ....See Detailed Company Profile  and Dividend History.

▶ Cerner (CERN): Cerner Corporation (Cerner), incorporated on October 6, 1986, is a supplier of healthcare information technology (HCIT). The Company offers a range of intelligent solutions and services that support the clinical, ....See Detailed Company Profile  and Dividend History.

▶ ChinaCache International (CCIH): ChinaCache International Holdings Ltd. (ChinaCache), incorporated on June 29, 2005, is a holding Company. The Company provides a portfolio of services and solutions to businesses, government agencies and other enterprises ....See Detailed Company Profile  and Dividend History.

... See Full List of All Stocks of EDP Services Sector.

Stock List of Other Technology Sub-sectors

▶ Stocks of Sector

▶ Stocks of Advertising Sector

▶ Stocks of Business Services Sector

▶ Stocks of Computer Communications Equipment Sector

▶ Stocks of Computer Manufacturing Sector

▶ Stocks of Computer Peripheral Equipment Sector

▶ Stocks of Computer Software-Prepackaged Software Sector

▶ Stocks of Computer Software-Programming and Data Processing Sector

▶ Stocks of Diversified Commercial Services Sector

▶ Stocks of EDP Services Sector

▶ Stocks of Electrical Products Sector

▶ Stocks of Electronic Components Sector

▶ Stocks of Electronic Gaming & Multimedia Sector

▶ Stocks of Industrial Machinery and Components Sector

▶ Stocks of Other Consumer Services Sector

▶ Stocks of Professional Services Sector

▶ Stocks of Radio TV Broadcasting Sector

▶ Stocks of Retail Computer Software and Equipment Sector

▶ Stocks of Semiconductors Sector

▶ Stocks of Software Sector

▶ Stocks of Technology Sector

▶ Stocks of Technology Services Sector

▶ Stocks of Telecommunications Equipment Sector


Stock List of Other Top-level Sectors

▶ Stocks of Sector

▶ Stocks of Basic Industries Sector

▶ Stocks of Basic Materials Sector

▶ Stocks of Capital Goods Sector

▶ Stocks of Communication Services Sector

▶ Stocks of Consumer Cyclical Sector

▶ Stocks of Consumer Defensive Sector

▶ Stocks of Consumer Durables Sector

▶ Stocks of Consumer Non-Durables Sector

▶ Stocks of Consumer Services Sector

▶ Stocks of Energy Sector

▶ Stocks of Finance Sector

▶ Stocks of Financial Services Sector

▶ Stocks of Health Care Sector

▶ Stocks of Industrials Sector

▶ Stocks of Miscellaneous Sector

▶ Stocks of Public Utilities Sector

▶ Stocks of Real Estate Sector

▶ Stocks of Services Sector

▶ Stocks of Technology Sector

▶ Stocks of Transportation Sector

▶ Stocks of Utilities Sector